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帕瑞昔布钠超前镇痛对腹腔镜胆囊切除术后镇痛的疗效观察 被引量：10

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摘要 目的:探讨帕瑞昔布钠超前镇痛对腹腔镜下胆囊切除患者术后镇痛的效果。方法:将90例ASAⅠ～Ⅱ级腹腔镜胆囊切除术患者随机分为A、B、C3组各30例。3组均采用丙泊酚、瑞芬太尼复合全麻,分别于麻醉诱导前(T1)、拔除气管导管前(T2)、拔管时(T3)、拔管后10min(T4),观察3组MAP、HR、SpO2,术毕拔管清醒后均采用芬太尼0.5μg/kg术后镇痛。采用VAS评分法评估患者术后7个不同时段疼痛程度并记录需追加芬太尼镇痛患者的时间间隔及追加次数;记录手术时间、麻醉苏醒时间及不良反应等情况。结果:3组不同时间点MAP、HR、SpO2比较,B、C组T2～T4各点MAP、HR较T1及A组显著升高,尤以C组为著(P<0.05),A、B两组患者在术后对应时段VAS评分均低于C组(P<0.05),且术后24h内需追加芬太尼镇痛的患者明显少于C组(P<0.05)。3组患者手术时间、麻醉苏醒时间及不良反应发生率差异无统计学意义(P>0.05)。结论:术前、术毕应用帕瑞昔布钠40mg可以产生较好的术后镇痛效果,同时可减少阿片类药物的应用。
作者 陈宏才 郑伟萍 应颖
机构地区 浙江省台州医院路桥院区麻醉科
出处 《实用医学杂志》 CAS 北大核心 2010年第24期4581-4583,共3页 The Journal of Practical Medicine
关键词 镇痛 帕瑞昔布钠 腹腔镜胆囊切除术
分类号 R614 [医药卫生—麻醉学]
  • 相关文献

参考文献7

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二级参考文献4

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共引文献20

同被引文献81

  • 1段砺瑕,李晓玲.氟比洛芬酯注射液的药理作用及临床应用[J].中国新药杂志,2004,13(9):851-852. 被引量：602
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引证文献10

二级引证文献103

实用医学杂志
2010年 第24期

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