摘要
抗病毒治疗已被公认为治疗乙型肝炎的重要措施,但抗乙型肝炎病毒(HBV)核苷(酸)类似物在妊娠及哺乳期妇女中应用的安全性尚有许多争议。本文综述了近年来有关核苷(酸)类似物在妊娠及哺乳期妇女中应用的文献,为HBV感染的妊娠及哺乳期妇女的抗病毒治疗和母婴阻断提供更多证据。
Antiviral therapy is generally acc pted as an important therapeutic measure for hepatitis B.But there are much controversies over the safety of anti-hepatitis B virus(HBV) nucleoside(nucleoti de) analogues used in pregnant and breastfeeding women.This article reviews the recent medical literatures regarding anti-HBV nucleoside(nucleotide) analogues used in pregnant and breastfeeding women in order to provide evidences of antiviral therapy in treating HBV-infected pregnant and breastfeeding women and pre venting mother-to-infant HBV vertical transmission.
出处
《药物不良反应杂志》
2010年第6期401-405,共5页
Adverse Drug Reactions Journal
关键词
乙型肝炎病毒
妊娠
哺乳
抗病毒治疗
核苷(酸)类似物
安全性
hepatitis Bvirus
pregnancy
breastfeeding
antiviral therapy
nucleoside(nucleotide) analogues
safety