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糖尿病肾病发病机制研究进展 被引量：22

Research on Pathogenesis of Diabetic Nephropathy
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摘要 糖尿病肾病(DN)是糖尿病(DM)最常见的慢性并发症,也是终末期肾病(ESRD)的主要原因,其治疗费用巨大。其发病机制主要涉及遗传易感性、糖代谢紊乱、肾血流动力学的改变、细胞因子、炎症机制已及氧化应激等方面。本文就以上作用机制的最新研究进展作一综述。 Diabetic nephropathy（DN）is the most common chronic complications of diabetes Mellitus（DM）,and is the most com-mon cause of end stage renal disease（ESRD）either.The annual cost of caring for patient with diabetic nephropathy is costly.There are multiple mechanisms contribute to the development of the disease,such as Genetic susceptibility,sugar metabolism disorders,renal hemodynamics,cytokines,inflammation and oxidative stress mechanisms and so on.These mechanisms above will be shown in this Review.
作者 赵芳芳 王季猛 程灿
机构地区 南华大学第二附属医院内分泌科
出处 《现代生物医学进展》 CAS 2010年第24期4796-4798,共3页 Progress in Modern Biomedicine
关键词 糖尿病肾病 发病机制 进展 Diabetes Nephropathy Pathogenesis Progress
分类号 R587.2 [医药卫生—内分泌]
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参考文献19

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二级参考文献15

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现代生物医学进展
2010年 第24期

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