摘要
目的比较替考拉宁和万古霉素治疗导管相关性感染革兰阳性球菌的疗效和不良反应。方法对40例应用国产替考拉宁治疗和36例应用万古霉素治疗导管相关性感染革兰阳性球菌患者的细菌清除率及不良反应进行统计学分析。结果国产替考拉宁和万古霉素治疗导管相关性感染革兰阳性球菌的疗效均较好,国产替考拉宁的有细菌清除率为87.5%;万古霉素的细菌清除率为88.9%;两者的细菌清除率比较差异无统计学意义(P>0.05);两种药物均有一定的药物不良反应发生,其中万古霉素组略多。结论国产替考拉宁和万古霉素是治疗导管相关性感染革兰阳性球菌的有效药物,国产替考拉宁较万古霉素药物不良反应更小。
OBJECTIVE To evaluate the efficacy and safety of teicoplanin and vancomycin on catheter-related infection Gram-positive（G＋）cocci.METHODS Forty catheter-related infection with G＋cocci were treated with teicoplanin,and Thirty-six were treated with vancomycin Therapeutic.The clearance rate of pathogens and side effect were compared.RESULTS The clearance rate of pathogens of teicoplanin was 87.5% and vancomycin was 88.9%.There was no significant difference between them.Both drugs had side effects.The side effect s of vancomycin was a little more than teicoplanin.CONCLUSION Both vancomycin and teicoplanin are effective drugs in the treatment of G＋ cocci in catheter-related infection.The side effects of teicoplanin are smaller than of vancomycin.
出处
《海峡药学》
2010年第12期114-115,共2页
Strait Pharmaceutical Journal
