摘要
目的探讨腹腔镜结直肠癌切除术对患者术后复发转移的影响。方法经病理诊断为结、直肠癌患者120例,随机分成腹腔镜手术组和开腹手术组。前者采用腹腔镜进行结直肠癌的根治手术,术中用结肠镜确定肿瘤部位和切除范围。后者采用开腹结直肠癌根治术。采用细胞学的方法检测肿瘤切除前后腹腔脱落癌细胞,采取门诊复查、电话和信件相结合方式测定术后肿瘤复发和转移率。比较两组病例在肿瘤切除前后腹腔脱落肿瘤细胞阳性率、术后3年复发转移率。结果两组患者肿瘤切除前、后腹腔脱落肿瘤细胞阳性率分别为15%(9/60),21.7%(13/60),χ2=0.891,P=0.345;25%(15/60),23.3%(14/60),χ2=0.046,P=0.831。两组患者术后3年局部复发转移率分别为7.0%,5.5%,χ2=0.117,P=0.733;10.5%,10.9%,χ2=0.004,P=0.948。结论腹腔镜结直肠癌手术没有导致患者术后的复发转移。
【Objective】To assess the effect of laparoscopic surgery on recurrence and metastasis of patients with colorectal carcinoma.【Methods】120 patients with colorectal cancer proven by pathologic histology were divided into two groups randomly,namely laparoscopy group （group A,n =60） and open operation group （group B,n =60）.In the group A,patients received laparoscopic curative operation,before the tumor tissues were resected the neoplasma was indicated by colonoscopy.In the group B,the patients underwent open curative operation.The disseminated cancer cells in peritoneal cavity were monitored respectively by cytological detection before and after resection.Recurrence and metastasis rates were calculated.【Results】In the group A,exfoliative cancer cells were found in 9 of 60 cases （15.0%） preoperation,and postoperation those were found in 15 of 60 cases （25.0%）.In the group B,those were found in 13 of 60 cases （21.7%）,and 14 of 60 cases （23.3%） respectively.There was not obvious difference statistically between group A and B （P =0.345,P =0.831）.Each group of patients was followed up 72 months after surgery.The recurrence and metastasis rate were 7.0% 10.5% and 5.5%,10.9% respectively （P =0.733,P =0.948）.【Conclusion】The laparoscopic operation may not increase the recurrence and metastasis rates of patients with colorectal cancer.
出处
《中国内镜杂志》
CSCD
北大核心
2010年第11期1167-1170,共4页
China Journal of Endoscopy
关键词
腹腔镜
结直肠癌
外科手术
laparoscopy
colorectal cancer
surgical operation
