摘要
目的探讨包含血肌酐值的CTP(CrCTP)评分对肝硬化住院患者预后的预测价值,并与CTP(Child-Turcotte-Pugh)评分和血肌酐值比较。方法将2 660例肝硬化住院患者分为存活组和死亡组。比较两组患者血肌酐值、CTP评分及CrCTP评分,并运用受试者工作特征(ROC)曲线及曲线下面积(AUC)评价其预测肝硬化患者预后的能力。结果肝硬化患者死亡组血肌酐值、CTP评分及CrCTP评分与存活组比较,差异均有统计学意义(P<0.01)。生存分析表明,血肌酐值、CTP评分及CrCTP评分在评估肝硬化患者预后的ROC曲线AUC分别为0.708、0.818和0.850。CrCTP评分评估住院肝硬化患者预后的AUC高于CTP评分和血肌酐值,CTP评分评估住院肝硬化患者预后的AUC高于血肌酐值,差异均有统计学意义(P<0.01)。结论血肌酐值、CTP评分及CrCTP评分均可预测肝硬化患者的预后,CrCTP评分评估效率优于血肌酐值和CTP评分。
Objective To explore the predictive values of creatinine-modified CTP（CrCTP）in assessment of prognosis of hospitalized cirrhosis patients,and compare with Child-Turcotte-Pugh（CTP） scores and serum creatinine（SCr）values. Methods A total of 2 660 hospitalized cirrhosis patients were divided into groups survival and death.SCr levels,CTP score,CrCTP score were compared,and receiver operating characteristic curve（ROC） and area under the curve（AUC） was used to assess their ability of prognosis prediction. Results Death group were significantly different from survival group in SCr,CTP score,CrCTP score（P0.01）.Survival analysis showed that ROC curve AUC of SCr,CTP score and CrCTP score were 0.708,0.818,0.850,respectively,in evaluation of prognosis of cirrhosis patients.AUC of CrCTP score was higher than that of CTP score and SCr,that of CTP higher than that of SCr,the difference was significant（P0.01）. Conclusion SCr,CTP score and CrCTP score can all predict the prognoses of cirrhosis patients,but CrCTP score superior to SCr and CTP score.
出处
《中国全科医学》
CAS
CSCD
北大核心
2011年第9期938-939,共2页
Chinese General Practice
关键词
肝硬化
CTP评分
预后
Liver cirrhosis
Child-turcotte-pugh score
Prognosis
