摘要
目的:观察七氟烷复合瑞芬太尼用于老年病人腹腔镜胆囊切除术(LC)的可行性及安全性。方法:ASA分级I～Ⅱ级腹腔镜下胆囊切除术老年患者60例,随机分为七氟烷+瑞芬太尼(SR组,n=30)和异氟烷+瑞芬太尼(IR组,n=30)组。两组病人术前用药及方法均相同。SR组吸入0.6MAC七氟烷I,R组吸入0.6MAC异氟烷,两组均复合持续输注2ug/kg/min瑞芬太尼。记录两组诱导前(T1)、CO2气腹前(T2)、气腹后10分钟(T3)及苏醒时(T4)的收缩压、舒张压、心率值;术毕停药后病人呼之睁眼时间、拔管时间;术后随访病人恶心呕吐、术中知晓情况。结果:两组术中不同时点SBP、DBP和HR比较,差异均无统计学意义。SR组睁眼时间、拔管时间均短于IR组。两组间比较有统计学意义(P<0.05)。结论:七氟烷相对异氟烷可控性更佳,术后苏醒更为迅速。
Objective：Study the feasibility and safety of sevoflurane and remifentanil in the elderly patient＇s laparoscopic cholecystectomy（LC）.Methods：ASA grade I ～Ⅱ stage laparoscopic cholecystectomy in elderly patients,60 patients were randomly divided into sevoflurane ＋ remifentanil（SR group,n=30） and isoflurane ＋ remifentanil（IR group,n=30） groups.the premedication,anesthesia induction agents and methods of the two groups of patients are the same.Sevoflurane inhale 0.6MAC SR group,IR group 0.6MAC isoflurane inhalation,and two groups were combined continuous infusion of remifentanil 2ug/Kg/min.The systolic blood pressure,diastolic blood pressure,heart rate before induction（T1）,CO2 pneumoperitoneum before（T2）,10 minutes after pneumoperitoneum（T3）,and wake up（T4） of the two groups were recorded;of surgery in patients after discontinuation of the wide open call eye time,extubation time;postoperative nausea and vomiting followed up the patients,intraoperative awareness situation.Results：of both groups at different time points in the SBP,DBP and HR,the difference was not statistically significant.The time of eye opening,tracheal extubation in SR group was shorter than that of the IR group.Between the two groups was statistically significant（P0.05）.Adverse reactions of the two groups are similar.Conclusion：Remifentanil Sevoflurane for Laparoscopic surgery combined can provide satisfactory anesthesia.Relatively,sevoflurane is better than isoflurane.
出处
《安徽卫生职业技术学院学报》
2011年第1期37-38,共2页
Journal of Anhui Health Vocational & Technical College
