摘要
目的:探讨缺氧缺血性脑病(HIE)患儿血清心肌酶谱的变化及其临床意义。方法:选择2006年1月～2008年1月期间于该院新生儿科就诊的120例HIE患儿为病例组,选择同期在该院产科分娩的正常足月新生儿120例为对照组。病例组于入院2、5、10、15天,对照组于分娩2日后抽血检测各项心肌酶。结果:①病例组各指标均高于对照组(P<0.05)。②将120例患儿按病情轻重再分为轻、中、重三个组,心肌酶谱各指标在各组间差异具有统计学意义(P<0.05)。③好转组各指标均低于恶化组(P<0.05)。好转组第2、5、10、15天各指标的水平呈逐渐下降趋势(P<0.05)。结论:HIE患儿存在心肌酶谱水平的升高,并且心肌酶谱的监测对于病情、预后、治疗情况判断均具有重要的意义。
Objective：To explore the change and clinical role of myocardium enzyme spectrum in HIE neonates. Methods：120 HIE neonates who were treated in our hospital during January 2006 to January 2008 were selected as the case group,and 120 healthy neonates were selected as the control group.Myocardium enzyme of the case group was tested when the neonates were in the hospital after 2,5,10 and 15 days,while the same parameters of the control group were tested 2 days after being born. Results：（1） Every parameter of the case group was higher than that of the control group（P0.05）.（2）In order to study the relationship of the disease state and the level of the enzyme,the children of the case group were divided into 3 groups.The results showed that the severe of the state,the higher of the level of enzyme.（3） Every parameters of the patients who became better was lower than that of the patients became worse（P0.05）.In light of the myocardium enzyme level of 2,5,10 and 15 days of the patients who became better,a tendency of decreasing was observation. Conclusion：In HIE neonates,the level of myocardium enzyme increase.Surveillance of myocardium enzyme can take a very important role in judgment of the disease state,prognosis,treatment of HIE.
出处
《中国妇幼保健》
CAS
北大核心
2011年第8期1168-1170,共3页
Maternal and Child Health Care of China
