摘要
０引言作为一类非生物必需元素，希土元素对生物体的作用机制及其对人体的长期毒性问题正日益受到人们的关注。为深入探讨这一问题，我们选择钙调素（Ｃａｌｍｏｄｕｌｉｎ，简称ＣａＭ）为研究对象。钙调素亦称钙调蛋白，是广泛存在于真核细胞中的重要钙结合蛋白。它不仅...
; The secondary structure of four kinds of Calmodulins (CaM), i.e. Brassica
Campestris Pollen Calmodulin (CaMBCP), Bovine Brain Calmodulin (CaMBB), Earthworm
Calcium Binding Protein (CaMCBP) and Earthworm New Calcium Binding Protein (CaMNCBP) in
thin film were determined through the technique of FTIR spectroscopic method and curvefitting.
The changes in the secondary structure of Calmodulin upon the addition of Ca\+\{2+\},
Eu\+\{3+\}, Tb\+\{3+\} and the activity of PDE enzyme were also measured, from which the effect
of rare earth ions on the conformation of Calmodulins were discussed.\=\;
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
1999年第4期509-512,共4页
Chinese Journal of Inorganic Chemistry
基金
国家自然科学基金
国家教委博士点基金
关键词
钙调素
二级结构
钙调蛋白
铕离子
铽离子
calmodulin\
\ \ secondary structure\ \ \ rare earth ion\ \ \ FTIR
