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Toll样受体4与运动的抗炎作用 被引量：3

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摘要 慢性炎症反应状态是一种常见的亚健康状态，常存在于衰老过程中及心血管疾病、代谢综合征等慢性疾病中。众多研究表明，长期有规律的运动锻炼可降低体内炎性因子水平，即运动具有抗炎作用，但其机制还不明了。Toll样受体4（TLR4）是TLRs家族的主要成员，可识别革兰氏阴性菌细胞壁的脂多糖（LPS），是介导LPS信号转导的主要受体，与炎症反应关系密切。研究显示运动锻炼可降低体内TLR4水平和TLR4mRNA表达，
作者 向剑锋 李之俊
机构地区 上海体育学院运动科学学院 浙江师范大学体育与健康科学学院 上海体育科学研究所
出处 《中国运动医学杂志》 CAS CSCD 北大核心 2011年第2期192-198,181,共8页 Chinese Journal of Sports Medicine
关键词 TOLL样受体4 运动锻炼 抗炎作用 TLR4mRNA表达 炎症反应状态 革兰氏阴性菌 慢性疾病 亚健康状态
分类号 R87 [医药卫生—运动医学]
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参考文献65

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二级参考文献63

共引文献35

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中国运动医学杂志
2011年 第2期

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