摘要
目的:观察氟比洛芬酯在甲状腺癌根治术中超前镇痛的有效性。方法:40例患者随机分成A、B两组,每组20例,均采用气管内插管全身麻醉。A组为试验组,在气管插管完成后,手术开始前静脉推注氟比洛芬酯100mg,B组为对照组于手术结束时静脉推注氟比洛芬酯100 mg。两组均未使用术后自控镇痛。分别于手术后0.5h、4h、8h、12h以及24h采用视觉模拟评分法(VAS)进行疼痛评分,并观察有关不良反应。结果:A组在术后24h的疼痛评分明显低于B组(P<0.05)。两组不良反应的发生率无显著差异。结论:氟比洛芬酯于甲状腺癌根治术术前使用能有效减轻术后疼痛。
Objective:To observe the preemptive analgesia effect of flurbiprofen axetil during radical operation of thyroid cancer.Methods: Fourty patients undergoing radical operation of thyroid cancer were randomly divided into two groups.Patients in both groups received general analgesia.After tracheal intubation,the patients in group A(n=20) received intravenous of flurbiprofen axetil 100mg before surgery,and those in group B(n=20) received intravenous of flurbiprofen axetil 100mg after suturing the incision.Patients controlled analgesia(PCA) was not used in two groups.Postoperative analgesia efficacy was assessed by Visual Analogue Scales(VAS) at 0.5h,4h,8h,12h and 24 h after extubation,and adverse reaction of flurbiprofen axetil were also observed.Results: VAS were significantly higher in group B during 24h after surgery compared with those in group A(P0.05).The adverse reactions were similar between two groups.Conclusion: Preemptive analgesia of flurbiprofen axetil can effectively alleviate the pain in radical operation of thyroid cancer.
出处
《现代肿瘤医学》
CAS
2011年第3期565-566,共2页
Journal of Modern Oncology
关键词
氟比洛芬酯
超前镇痛
甲状腺癌根治
flurbiprofen axetix
preemptive analgesia
radical operation of thyroid cancer