摘要
目的:通过与羟氯喹治疗方案的对比,客观评价生津方治疗干燥综合征(SS)的疗效和安全性。方法:入选46例符合原发性干燥综合征诊断,以及中医辨证符合阴虚内燥标准的病人,分为中药组23例,以生津方治疗;西药组23例,以羟氯喹治疗。疗程3个月。结果:中药组总有效率65.22%,西药组总有效率43.48%,两者无明显统计学差异(P>0.05)。中药组患者自我评分与治疗前比较,差异有统计学意义(P<0.05),其中,在缓解口干、口腔烧灼感症状方面疗效显著(P<0.01)。结论:生津方可以改善干燥综合征患者自觉症状,尤其在缓解口干、口腔烧灼感症状方面疗效显著。
Objectives：Through the control experiment with hydroxychloroquine,make the objective evaluation about the curative effect and security of Sheng Jin prescriptions.Method：Forty six patients with primary sjogren＇s syndrome（pSS） and Yin asthenia internal dryness were divided into two groups,each group had twenty three patients.They have differently been treated by ShengJin prescriptions and hydroxychloroquine.The period of treatment were both three months.Result：The clinical effective rate of TCM was 65.22%,and the western medicine was 43.48%,the result had no statistical significance（P〉0.05）.After treatment,the self-estimate of the patients with Chinese medicine were better,the result had statistical significance（P〈0.05）,especially in alleviating the thirst and the mouth causalgia（P〈0.01）.Conclusion：ShengJin prescriptions can improve the self-conscious symptoms of the patients with pSS,especially in alleviating the thirst and the mouth causalgia.
出处
《成都中医药大学学报》
2011年第1期30-32,共3页
Journal of Chengdu University of Traditional Chinese Medicine
基金
"十一五"国家科技支撑计划资助项目(编号:2007BAI20B055)
关键词
干燥综合征
生津方
羟氯喹
临床研究
Sjogren＇s syndrome
ShengJin prescriptions
hydroxychloroquine
clinical research
