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缺血修饰白蛋白在急性胸痛患者鉴别诊断中的应用价值 被引量：3

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摘要 目的探究IMA检测对急性胸痛患者的鉴别诊断价值,以利于临床对心源性胸痛的早期诊断。方法通过检测88例以胸痛症状来我院急诊患者的IMA水平,根据患者最终确定的临床诊断,计算IMA预测心源性胸痛的敏感性和特异性,由此分析IMA对于急性胸痛患者鉴别诊断的意义。结果研究发现所有88例入选患者中,心源性胸痛54例,IMA均值高达(99.56±18.67)U/ml,非心源性胸痛患者34例,IMA均值为(49.35±11.22)U/ml。两者差异有统计学意义(P<0.05)。IMA检测的灵敏度、特异度和阴性预测价值均较高,分别为94.4%、79.4%和90%。结论急性胸痛患者IMA的检测可以高效率地鉴别心源性及非心源性胸痛,尤其灵敏度及阴性预测值较高,能显著减少心源性胸痛患者的漏诊,降低由此而产生的医疗风险。
作者 张宏伟 杨望君
机构地区 湖南省岳阳市三人民医院
出处 《实用预防医学》 CAS 2011年第3期515-517,共3页 Practical Preventive Medicine
关键词 缺血修饰白蛋白 急性胸痛 鉴别诊断
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献5

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同被引文献21

  • 1龙国文,胡佳林.缺血修饰白蛋白——新的心肌缺血生化标志物[J].国际检验医学杂志,2006,27(1):77-80. 被引量：10
  • 2A1 Suwaidi J, AI Habib K, Singh R, et al. Tobacco modalities used and outcome in patients with acute coronary syndrome: an observational report[J]. Postgrad Med J,2012,88(1044):566- 574.
  • 3Van Belle E, Dallongeville J, Vicaut E, et al. Ischemia-modified albumin levels predict long-term outcome in patients with acute myocardial infarction. The French Nationwide OPERA study [J]. Am Heart J,2010,159(4):570-576.
  • 4Anderson JL,Adams CD,Antman EM. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction[J].Journal of the American College of Cardiology,2007,(07):e1-157.
  • 5Westwood M, van Asselt T, Ramaekers B, et al . High-sen- sitivity troponin assays for the early rule-out or diagnosis of a- cute myocardial infarction in people with acute chest pain: a systematic review and cost-effectiveness analysis [J]. Health Technol Assess, 2015, 19(44) ~ 1-234.
  • 6Alpert JS, Thygesen K, Antman E.Myocardial Infarction rede- fined-a consensus document of the joint european societyedety of cardiology/american college of cardiology committee for the redefinition of myocardial infarction ~J]. J Am Coll Cardiol, 2000,36(3) :959-969.
  • 7Braunwald E, Antman EM, Beasley JW, et al .ACC/AHA guidelines for the management of patients with unstable angi- na and non-ST segment elevation myocardial infarction [J]. J Am Cell Cardiol, 2000, 36(3), 970-1062.
  • 8张健,胡大一,王显,郭实,杨士伟,张守彦,石宇杰,徐威,李晓明,路敏.在急诊科设立胸痛中心对胸痛患者诊疗时间的影响[J].中华老年多器官疾病杂志,2009,8(5):439-441. 被引量：31
  • 9马芳芳,王厚照,沈晓丽,林立方.急性脑梗死致心脏损伤患者血清缺血修饰白蛋白的变化[J].中华实用诊断与治疗杂志,2010,24(4):321-323. 被引量：5
  • 10郭宗强,王晓菲.缺血修饰白蛋白诊断急性心肌缺血价值[J].中华实用诊断与治疗杂志,2010,24(5):511-513. 被引量：14

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实用预防医学
2011年 第3期

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