摘要
目的 探讨稳心颗粒联合丹红注射液治疗冠心病频发室性早搏的疗效。方法95例稳定型冠心病频发性室性早搏患者，随机分为治疗组（48例）和对照组（42例）。治疗组采用稳心颗粒＋丹红注射液＋胺碘酮治疗；对照组采用胺碘酮治疗，对比观察两组的疗效，同时监测其对血压、心率、C反应蛋白（hs—CRP）及QT离散度（QTd）的影响。结果用药后两组室性早搏发作次数均明显减少，与对照组相比较，治疗组室性早搏减少更明显，其差异具有显著性（P〈0．05）；治疗组hs—CRP水平明显低于对照组；2组QTd均较治疗前明显下降，但两组之间无统计学差异（P〉0．05）；两组均未出现严重副作用。结论稳心颗粒联合丹红注射液对冠心病频发室性早搏具有明显疗效，其机理可能与降低hs—CRP和QTd有关。
Objective To investigate the effects of wen xin particle combined with dan hong injection on frequent premature ventricle in patients with stable coronary heart disease （ CHD）. Methods The cases with frequent premature ventricle were randomizedly divided into observation group and control group. The two groups received the treatment of amiodarone, and the observation group received the treatment of wen xin particle combined with dan hong injection. We observed and record the changes of premature ventricle, blood pressure,heart rate, CRP and QTd. Resuits Premature ventricular contractions after treatment by wen xin particle combined with dan hong injection were lower than that before treatment. The observation group had an advantage over the control group in improving CRP. The QTd was reduced in both groups and there was no difference between them （ P 〉 0.05 ）. Conclusion Wen xin particle combined with dan hong injection can improve frequent premature ventricle in patients with stable CHD, which maybe relate to the reduction of CRP and QTd.
出处
《医学新知》
CAS
2011年第1期15-17,共3页
New Medicine
关键词
稳心颗粒
丹红注射液
冠心病
室性早搏
dan hong injection
wen xin particle
premature ventricle
CHD
