摘要
糖尿病患者甲状腺功能异常的发生率明显高于普通人群,主要表现为亚临床甲状腺功能减退,目前机制尚不清楚,可能与甲状腺自身抗体及葡萄糖毒性有关。糖尿病合并亚临床甲状腺功能减退者,总胆固醇和低密度脂蛋白明显升高,血压升高,左心室功能受损,心血管事件的风险增加,糖尿病视网膜增殖性病变及重度非增殖性病变增多。此外,尚可能影响糖尿病患者的胰岛B细胞功能以及认知能力。
The incidence of thyroid dysfunction in diabetics is significantly higher than that in the general population,mainly for subclinical hypothyroidism.The pathogenesis is unclear currently.May be related to thyroid antibodies and glucotoxicity.The diabetes mellitus combined with subclinical hypothyroidism person,their total cholesterol and low density lipoprotein increased significantly,blood pressure elevated,and left ventricular dysfunctioned,the risks of cardioascular events increased,diabetes retinal hyperplastic lesions and severe hyperplastic lesions increased.In addition,it may be influence the pancreatic B cell function and cognitive abilities of diabetics.
出处
《医学综述》
2011年第6期899-902,共4页
Medical Recapitulate
