摘要
目的:探讨全凭静脉麻醉下应用脑电双频谱指数(BIS)监测术中知晓的发生情况,评价BIS监测对术中知晓的预防作用。方法:丙泊酚全凭静脉麻醉下行择期手术患者300例,随机分成A、B两组(n=150)。两组患者均进行BIS监测,A组根据BIS值调控麻醉深度,确保麻醉期间BIS值<60;B组术中遮蔽BIS值,根据经验调控麻醉深度。记录两组患者麻醉诱导、手术开始、麻醉停药、手术结束、麻醉苏醒、拔管时BIS值及术中知晓的发生情况。结果:两组患者基础BIS值、诱导结束时、清醒时及拔管时BIS值比较差异无统计学意义(P>0.05),手术开始时、麻醉维持和麻醉结束时BIS值比较差异有统计学意义(P<0.05)。A组无知晓病例及怀疑知晓病例。B组无知晓病例,但存在2例怀疑知晓病例,2组怀疑知晓率比较差异有统计学意义(P<0.05)。结论:全凭静脉麻醉时采用BIS监测能够维持合适的麻醉深度,预防术中知晓的发生。
Objective To investigate the incidence of intraoperative awareness using bispectral index（BIS） monitoring and evaluate the preventive effect of BIS on intraoperative awareness under total intravenous anesthesia.Methods 300 patients undergoing total intravenous anesthesia with BIS monitoring were randomly divided into two groups：group A and group B（n=150）.In group A,the depth of anesthesia was regulated lower than 60 according to BIS.While in group B,the BIS monitor was covered and the depth of anesthesia was modulated according to the experience of the anesthesiologist.The BIS values were recorded at the time of anesthesia induction,beginning of operation,anesthesia withdrawal,end of operation,recovery of anesthesia and extubation.Results The basic BIS and BIS values at the time of anesthesia induction,awake and extubation had no significant differences between two groups（P〉0.05）.The BIS values at the time of beginning of operation,anesthesia maintenance and anesthesia withdrawl in group B were significantly higher that those in group A（P〈0.05）.The patients with awareness and suspected of awareness were not found in group A.The patients with awareness were not found in group B but there were two patients suspected of awareness.The incidence of patients suspected of awareness had significant difference between two groups（P〈0.05）.Conclusion BIS monitoring during total intravenous anesthesia could maintain the appropriate depth of anesthesia and prevent intraoperative awareness.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2011年第2期308-311,共4页
Journal of Jilin University：Medicine Edition
基金
吉林省科技厅科技发展计划项目资助课题(200905133)
关键词
脑电双频谱指数
知晓
麻醉
全身
bispectral index； intraoperative awareness； anesthesia,general
