摘要
肥胖与包括性激素异常在内的内分泌紊乱密切相关,因为激素的分泌方式和(或)代谢途径或其在靶器官的作用水平在肥胖的状态下发生了改变,长期以来,这些改变被认为继发于肥胖,肥胖影响性激素的水平,但是,肥胖与性激素在体内的相互作用的关系相当复杂。近年来的研究揭示性激素的变化也可能是在脂肪的分布、不同类型的肥胖的病理生理及其相关的代谢异常中起着重要的作用。
Obesity is closely related to endocrine disorders including sex hormone abnormalities. Over a long time, changes in the secretory pathways and/or metabolism of hormones, and altered hormone-related effects at the level of target organs have been considered to be secondary to obesity. While obesity affects sex hormone levels, the interaction between obesity and sex hormones in the body may actually be very complicated. In recent years, stud- ies have revealed that aherations in sex hormone may also play a major role in the distribution of adipose tissues, pathophysiology of obesity phenotypes,and metabolic abnormalities associated obesity.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2011年第4期257-259,共3页
Chinese Journal of Practical Internal Medicine
关键词
肥胖
性激素
脂肪组织分布
obesity
sex hormone
distribution of adipose tissue
