摘要
目的探讨胚胎停育患者蜕膜和绒毛组织中B淋巴细胞刺激因子(BAFF)的表达与胚胎停育的关系。方法随机选择早孕胚胎停育患者30例作为实验组,正常早孕人工流产者30例为对照组。用免疫组化(二步法)法测定蜕膜及绒毛中BAFF的表达情况。结果 BAFF在所有标本中都有表达,但胚胎停育组蜕膜中BAFF的表达均低于对照组(P<0.05),胚胎停育组蜕膜血管内皮中则无表达。结论 BAFF与胚胎停育有一定的关联,可能是导致胚胎停育的原因之一。
Objective To study the correlation between the expression of B lymphocyte activating factor in decidual and chorionic membranes and early spontaneous abortion.Methods Thirty women with early spontaneous abortion served as an experimental group and 30 women who had artificial abortion for normal early pregnancy served as a control group.Expression of B lymphocyte activating factor in decidual and chorionic membranes was detected by immunohistochemistry.Results B lymphocyte activating factor was expressed in all samples of decidual and chorionic membranes.However,its expression level in decidual membrane was lower in experimental group than in control group（P0.05）.B lymphocyte activating factor was not expressed in angioendothelium of experimental group.Conclusion B lymphocyte activating factor is associated with early spontaneous abortion and may be one of the reasons for early spontaneous abortion.
出处
《军医进修学院学报》
CAS
2011年第4期383-385,共3页
Academic Journal of Pla Postgraduate Medical School
