摘要
目的了解脑卒中后肺部感染铜绿假单胞菌(PAE)的耐药特点,为临床合理用药提供科学依据。方法对2009年1月-2010年6月脑卒中后发生肺部感染的住院患者临床资料进行回顾性分析。结果患者的感染性痰标本中分离出PAE共92株,具有多药耐药性,耐药率>90.0%有青霉素类、头孢菌素类、呋喃妥因和磺胺甲噁唑/甲氧苄啶共9种,<30.0%的有美罗培南、亚胺培南、哌拉西林/他唑巴坦、环丙沙星,分别为19.5%、20.6%、25.0%、17.4%。结论了解医院PAE的耐药特点,对合理选用抗菌药物,有效地控制脑卒中后PAE引起的肺部感染具有十分重要的临床意义。
OBJECTIVE To learn about the drug resistance of Pseudomonas aeruginosa in cerebral stroke patients with pulmonary infection,and provide the scientific basis for clinical medication.METHODS From Jan 2009 to Jun 2010,Clinical data for hospitalized patients with the lung infection after cerebral stroke was retrospectively analyzed.RESULTS A total of 92 strains of PAE were isolated from infected sputum of the patients.PAE was multidrug-resistant.The drug resistant rates of PAE to nine kinds of antibiotics,including penicillins,cephalosporins,nitrofurantion and Sulfamethoxazole/trimethoprim,exceed 90.0%,the drug resistance rates to meropenem（19.5%）,imipenem（20.6%）,piperacillin/tazobactam（25.0%） and ciprofloxacin（17.4%）were less than 30.0%.CONCLUSION It has great clinical significance to effectively control the pulmonary infection caused by PAE after cerebral stroke and reasonably use antibiotics through understanding drug resistance characteristics of PAE.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第8期1683-1684,共2页
Chinese Journal of Nosocomiology
关键词
脑卒中
肺部感染
铜绿假单胞菌
耐药性
Cerebral stroke
Pulmonary infection
Pseudomonas aeruginosa
Drug resistance
