摘要
目的了解新疆恶性肿瘤患者医院假丝酵母菌属感染现状及其耐药状况。方法对医院住院恶性肿瘤患者送检的7997份标本中假丝酵母菌属的分离鉴定及药敏试验结果进行分析。结果 697份标本检出假丝酵母菌属,阳性率为8.7%;其中以白色假丝酵母菌最为常见,占60.5%;医院分离的假丝酵母菌属未发现对两性霉素B耐药的菌株;5-氟胞嘧啶对临床常见假丝酵母菌属具有较强的抗菌活性,克柔假丝酵母菌、光滑假丝酵母菌对氟康唑、伊曲康唑的耐药性较高。结论白色假丝酵母菌是恶性肿瘤患者假丝酵母菌感染的主要类型,应根据药敏结果合理用药。
OBJECTIVE To investigate the conditions of candida infection and drug resistance in malignant tumor patients in Xinjiang.METHODS A total of 7997 clinical samples were collected from malignant tumor patients.Their resistance to antifungal agents were analyzed.RESULTS The incidence of candida infection was 8.7%.C.albicans was the major fungus and accounted for 60.5%.All candidas were susceptive to amphotericin B（AMB）,and 5-fucitosine（5-FC） had high susceptibility to usual candidas.C.krusei and C.glabrata showed high resistance rate to fluconazole and itraconazole.CONCLUSION The main pathogens causing candida infection in malignant tumor patients is C.albicans.The results of antifungal susceptibility test can provide the foundation for the rational use of antibiotics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第8期1706-1707,共2页
Chinese Journal of Nosocomiology
关键词
恶性肿瘤
假丝酵母菌属
耐药性
Malignant tumor
Candida
Antibiotic resistance
