摘要
微小RNA(miRNA)是长度为22nt左右的非编码RNA,具有转录后调节的功能,对细胞的增殖、凋亡和分化起到重要作用。胃癌是世界第四大常见肿瘤,高居癌症死亡的第二位。越来越多的研究表明miRNA在肿瘤中起着原癌基因或抑癌基因的作用,本文将阐述miRNA与胃癌的关系的研究进展。
microRNA is a length of about 22nt non-coding RNA,with the function of post-transcriptional regulation of cell proliferation,apoptosis and differentiation.Gastric cancer is the fourth most common cancer,ranking second in cancer deaths.Increasing numbers of studies have shown that miRNA plays important role as tumor proto-oncogenes or tumor suppressor gene.This article will set out the relationship between miRNA and gastric cancer are reviewed.
出处
《现代生物医学进展》
CAS
2011年第5期982-985,共4页
Progress in Modern Biomedicine