摘要
目的:评估加兰他敏胶囊治疗老年性痴呆和单纯性记忆障碍的疗效。方法:42 例老年性痴呆和32 例单纯性记忆障碍病人入组,其中37 例( 男性22例,女性15 例,年龄63 a ±s 8 a) 用加兰他敏胶囊10 m g ,po ,qid ,另37 例( 男性22 例,女性15 例,年龄65 a ±7 a) 用吡拉西坦胶囊800 m g ,po ,tid ,疗程均为8 w k 。结果:加兰他敏组总有效率70 % ,吡拉西坦组为40 % ( P< 0 .01) ,加兰他敏组痴呆病人日 常生活功能也较治疗前有明显提高( P< 0 .01) ,该药不良反应轻。结论:加兰他敏胶囊治疗老年性痴呆安全有效。
AIM: To evaluate the therapeutic effects of galantamine on senile dementia and benign senescent forgetfulness. METHODS: Thirty_seven patients with senile dementia and benign senescent forgetfulness in treatment group(M22, F 15, age 63 a±s 8 a) were treated with galantamine 10 mg, po, qid for 8 wk; other 37 patients (M 22, F 15,age 65 a±7 a) were treated with piracetam 800 mg, po, tid. RESULTS: The total effective rates of galantamine and piracetam were 70% and 40%, respectively(P<0.01). Daily life function of patients with senile dementia was improved after galantamine treatment. Adverse reactions of galantamine was mild. CONCLUSION:Galantamine has a safe and therapeutic effect on senile dementia.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
1999年第4期198-200,共3页
Chinese Journal of New Drugs and Clinical Remedies
关键词
加兰他敏
毗拉西坦
老年性痴呆
治疗
galanthamine
piracetam
senile dementia
memory disorders.