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吸烟对急性心肌梗死患者临床疗效的分析

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摘要 目的:通过对急性ST段抬高型心肌梗死(ASTEMI)晚期再灌注吸烟与非吸烟患者的出院12个月随访,探讨吸烟对ASTEMI的终点事件、心功能预后的影响。方法:选择ASTEMI住院患者149例。根据是否吸烟分为两组:吸烟组86例;非吸烟组63例。分别记录两组的临床资料,出院后12个月进行电话随访,预约心动超声检查及6min步行试验。结果:1吸烟组较非吸烟组主要终点事件心源性病死率明显升高有显著性差异(P<0.05);吸烟组较非吸烟组次要终点事件非致命性心肌梗死、心绞痛再入院率明显升高有显著性差异(P<0.05)。2非吸烟组较吸烟组心功能左室射血分数(LVEF)有明显改善,左室舒张末内径(LVDd)明显缩小(P<0.01),6min步行试验有显著提高(P<0.05)。结论:1吸烟增加急性心肌梗死患者病死率和再入院率;2吸烟使心功能明显下降。
出处 《陕西医学杂志》 CAS 2011年第4期418-419,共2页 Shaanxi Medical Journal
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  • 1血脂康调整血脂对冠心病二级预防研究协作组.中国冠心病二级预防研究[J].中华心血管病杂志,2005,33(2):109-115. 被引量:222
  • 2宿英英,孟琛,孟家眉,杨培洁.脑梗塞心理社会生物因素的综合研究[J].中国心理卫生杂志,1994,8(1):13-15. 被引量:7
  • 3郑心田,李广平.1961例急性心肌梗死发病年龄和性别分布分析[J].临床心血管病杂志,2007,23(4):312-313. 被引量:17
  • 4蒋健.老年性心肌梗塞[J].上海医学,1982,5(9):518-518.
  • 5Bozzo J, Heras M, Ordinas A, et al. Impaired antiplatelet effects of aspirin associated with hypoxia and ATP release from erythrocytes. Studies in a system with flowing human blood[J]. Eur J Clin Invest, 1999,29 (5) : 438-444.
  • 6Roberts W, Riba R, Homer-Vanniasinkam S, et al. Nitric oxide specifically inhibits integrin-mediated platelet adhesion and spreading on collagen[J]. J Thromb Haemost, 2008, 6 (12) ..2175-2185.
  • 7Shimasaki Y, Saito Y, Yoshimura M, et al. The effects of long-term smoking on endothelial nitric oxide synthase mRNA expression in human platelets as detected with realtime quantitative RT-PCR[J]. Clin Appl Thromb Hemost, 2007,13(1) :43-51.
  • 8Nakayama M, Yasue H, Yoshimura M, et al. T-786 C mutation in the 5"-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm[J]. Circulation, 1999,99 (22) : 2864-2870.
  • 9Takajo Y,Ikeda H,Haramaki N, et al. Augmented oxidative stress of platelets in chronic smokers. Mechanisms of impaired platelet-derived nitric oxide bioactivity and augmented platelet aggregability[J]. J Am Coil Cardiol, 2001,38 (5) : 1320-1327.
  • 10Sawada M, Kishi Y, Numano F, et al. Smokers lack morning increase in platelet sensitivity to nitric oxide[J]. J Cardiovasc Pharmacol, 2002,40 (4) : 571-576.

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