摘要
The electrocatalysis oxidation of guanosine-5＇-monophosphate （GMP） was investigated on Mg-AI layered double hydroxide （LDH） functionalized with sodium dodecyl sulfate （SDS） and room temperature ionic liquid （RTIL） modified glass carbon electrode （GCE）. The cyclic voltammogram of GMP on the modified electrode （RTIL/ LDH-SDS/GCE） exhibited a well defined anodic peak at 1.091 V in 0.2 moloL ^-1 pH 4.4 acetate buffer solution. The GMP oxidation was enhanced in the presence of anionic surfactant in the films. The results suggest that the surfactant molecules intercalate the LDH layers to preconcentrate GMP molecules and the RTIL showed good ionic conductivity. The experimental parameters were optimized, the kinetic parameters were investigated and the probable oxidation mechanism was proposed. Under the optimized conditions, the oxidation peak current was proportional to GMP concentration in the range from 5.0 × 10^-7 to 1.0×10^-4 mol·L ^-1with the correlation coefficient of 0.9987 and the detection limit was 1.0 × 10 7 mol·L^-1, The RTIL/LDH-SDS/GCE showed a good electrochemical response to the oxidation of GMP and would be developed into a new biosensor.
The electrocatalysis oxidation of guanosine-5＇-monophosphate （GMP） was investigated on Mg-AI layered double hydroxide （LDH） functionalized with sodium dodecyl sulfate （SDS） and room temperature ionic liquid （RTIL） modified glass carbon electrode （GCE）. The cyclic voltammogram of GMP on the modified electrode （RTIL/ LDH-SDS/GCE） exhibited a well defined anodic peak at 1.091 V in 0.2 moloL ^-1 pH 4.4 acetate buffer solution. The GMP oxidation was enhanced in the presence of anionic surfactant in the films. The results suggest that the surfactant molecules intercalate the LDH layers to preconcentrate GMP molecules and the RTIL showed good ionic conductivity. The experimental parameters were optimized, the kinetic parameters were investigated and the probable oxidation mechanism was proposed. Under the optimized conditions, the oxidation peak current was proportional to GMP concentration in the range from 5.0 × 10^-7 to 1.0×10^-4 mol·L ^-1with the correlation coefficient of 0.9987 and the detection limit was 1.0 × 10 7 mol·L^-1, The RTIL/LDH-SDS/GCE showed a good electrochemical response to the oxidation of GMP and would be developed into a new biosensor.
基金
Project supported by the National Natural Science Foundation of China （No. 201075078） and the Natural Science Foundation of Shandong Province （No. ZR2010BM05）.
