摘要
目的 探讨阿尔茨海默病（Alzheimer＇s disease,AD）可能的危险因素.方法采用以人群为基础按1：2的比例进行年龄、性别、文化程度、职业性质相匹配的病例对照研究,病例为调查的人样本群中确诊的AD患者81例,对照为同人群中符合匹配条件的认知功能正常者162例.用SAS8.2软件进行单因素分析和非条件Logistic回归分析.结果Logistic回归分析显示,冠心病、脑卒中和高血脂者患AD的危险较大,OR值（95%CI）分别为2.441（1.282～4.641）、1.875（1.015～3.464）、1.770（0.976～3.199）.结论冠心病、脑卒中、高血脂可增加AD患病的危险性.
Objective To study the risk factors of Alzheimer＇s disease in urban community of Suzhou. Methods A population based on 1：2 matched case-control study was conducted,including 81 AD patients from the same population matched for age,sex and education as controls.Data was analysed using logistics regression analysis with SAS8.2 soft-ware. Results Analysis showed that coronary heart disease,stroke and hyperlipidemia were found to be correlated with AD. The OR value were 2.441 （1.282 - 4.641 ）, 1.875（1.015 - 3.464）, 1.770（0.976 - 3.199）. Conclusion Coronary heart disease,stroke and hyperlipidemia may be the independent risk factors of AD.
出处
《中国血液流变学杂志》
CAS
2011年第1期40-42,共3页
Chinese Journal of Hemorheology
