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慢性心衰患者血清脑利钠肽前体水平与心功能的相关性分析 被引量:2

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摘要 目的探讨慢性心衰患者血清脑利钠肽前体(NT-proBNP)水平与不同NYHA心功能分级、左室射血分数(LVEF)、左室舒张期末内径(LVEDd)的相关性。方法 42例心力衰竭住院患者,使用酶联免疫法测定其血清NT-proBNP水平,超声心动图测定LVEF及LVEDd,分析患者NT-proBNP水平与不同心功能分级及上述指标的相关性。结果 (1)不同NYHA心功能分级组患者血清NT-proBNP水平(pg/ml)差异有统计学意义[Ⅰ级:162.5(128.0,633.0),Ⅱ级:1 202.5(587.0,2350.0),Ⅲ级:3 374.0(2 169.0,4 442.0),Ⅳ:10 403.5(7 241.0,17 697.0),P〈0.05~〈0.01],其水平与心功能分级呈正相关(r=0.797,P〈0.000 1);(2)NT-proBNP与LVEF呈负相关(r=-0.438,P〈0.000 1);(3)NT-proBNP与LVEDd呈正相关(r=0.437,P〈0.000 1)。结论 NT-proBNP测定是临床诊断心力衰竭的有效辅助方法之一,总体上可反映心力衰竭的严重程度。
作者 李海英
出处 《中国误诊学杂志》 CAS 2011年第9期2112-2112,共1页 Chinese Journal of Misdiagnostics
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