摘要
目的:探讨临床上系统性红斑狼疮患者血清免疫检查指标和意义。方法:选择我院2009年1月至2010年10月收治的系统性红斑狼疮患者36例,临床常规应用甲基强的松龙,测定治疗前后血清检查抗核抗体、抗双链DNA抗体、免疫球蛋白和补体3水平、肿瘤坏死因子-α和白介素-6含量。与同期体检健康人群血清指标进行比较。结果:系统性红斑狼疮患者血清ANA与抗-dsDNA阳性检出率分别为94.4%和69.4%。患者血清中IgG、C3、TNF-α和IL-6含量明显区别于对照组,经过激素治疗后研究组患者血清各项指标均趋于正常水平。结论:血液免疫检查有助于系统性红斑狼疮的诊断和监测患者病情的转归。
Objective： To discuss the immunologic test index and significance of systemic lupus erythematosus. Method： 36 patients with systemic lupus erythematosus in our hospital from Jan. 2009 to Oct. 2010 were subjected to methylprednisolone, and detected serum antinuclear antibody, anti-dsDNA, immune globulin and C3 complement, tumor necrosis factor-or and interleukin-6 level. The same serum indexes of healthy persons also v-ere detected. Result： Serum antinuclear antibody and anti-dsDNA in lupus erythematosus patients was 94.4 percent and 69.4 percent respectively. Serum immune globulin and C3 complement, tumor necrosis factor-α and interleukin-6 level were significantly different with normal group. However, these indexes were trend to normal levels. Conclusion： Blood immunologic test is benefit for diagnosing and turnover of systemic lupus erythematosus.
出处
《河北医学》
CAS
2011年第4期492-494,共3页
Hebei Medicine
关键词
红斑狼疮
免疫
IL-6
Systemic lupus erythematosus
Immunization
IL-6
