期刊文献+

COX-2及其抑制剂与乳腺癌关系的研究进展 被引量:8

下载PDF
导出
摘要 环氧化酶(cyclooxygenase,COX),是催化花生四烯酸(AA)产生前列腺素族(PGs)的关键限速酶,以COX-1和COX-2两种同工酶的形式存在。COX-1是结构型酶,体内大多数正常组织都表达,参与维持机体正常的生理机能。而COX-2是诱导型酶,
作者 江丹贤 吴华
出处 《河北医学》 CAS 2011年第4期537-539,共3页 Hebei Medicine
基金 广东省科技计划项目(专题编号2009B06700075)
  • 相关文献

参考文献3

二级参考文献31

  • 1Robert W,Memurray MD,Kenneth J,et al. Cox-2 inhibitors: today and tomorrow[J].Am J Med Sci,2002;323(4) :181-189.
  • 2Sharpe CR, Collet JP, McNutt M, et al. Nested casecontrol study of the effects of non-steroidal anti-inflammatory drugs on breast cancer risk and stage[J]. Br J Cancer, 2000;83(1):112-120.
  • 3Harris RE, Alshafie GA, Abou-Issa H, et al. Chemoprevention of breast cancer in rats by celecoxlib, a eyclooxygenase 2 inhibitor[J]. Cancer Res, 2000 ; 60(8) : 2101 - 2103.
  • 4Nakatsugi S, Ohta T, Kawamori T, et al. Chemoprevention by nimesulide, a selective cyclooxygenase 2 inhibitor, of 2-amino-lmethy-6-phenylimidazo[4,5 b]pyridine(PhIP) -induced mammary gland carcinogenesis in rats[J]. Jpn J Cancer Res,2000;91(9) :886-892.
  • 5Tsujii M, Kawano S, DuBois RN. Cyclooxygenases-2 expression in human colon cancer cells increases metastatic potential[J]. Proc Natl Acad Sic USA, 1997, 94 (7):3336-40.
  • 6Soslow RA, Dannenberg AJ, Rush D, et al. COX-2 is expressed in human pulmonary, colonic, and mammary tumors[J]. Cancer, 2000, 89 (12) :2637-45.
  • 7Ristimaki A, Nieminen O, Saukkonen K, et al. Expression of cyclooxygenase-2 in human transitional cell carconima of the urinary bladder[J]. Am J Pathol, 2001,158 (3) :849-53.
  • 8Fujiwaki R, Iida K, Kanasaki H, et al. Cyclooxygenase-2 expression in endometrial cancer: correlation with microvessel count and expression of vascular endothelial growth faotor and thymidine phosphorylase[J]. Hum Pathol, 2002,33 (2) : 213-9.
  • 9Costa C, Soares R, Reis-Filho JS, et al. Clyclooxygenase-2 expession is associated with angiogenesis and lymph node metastasis in human breast cancer[J]. J Clin Pathol, 2002,55 (6) :429-34.
  • 10Tavassoli FA, Devilee P. World Health Organization classification of tumors. Pathology and genetics, tumors of the breast and female genital organs[M]. Lyon: IARC Press,2003:63-73.

共引文献22

同被引文献73

引证文献8

二级引证文献25

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部