摘要
目的探讨消旋卡多曲,西咪替丁联合治疗婴幼儿轮状病毒肠炎的疗效和安全性。方法采用随机对照的方法,将76例轮状病毒肠炎患者分为2组,治疗组40例,对照组36例,两组均用于补液,调整饮食,利巴韦林抗病毒等综合治疗。治疗组给予消旋卡多曲口服,西咪替丁滴注,对照组予思密达口服,比较两组疗效及安全性。结果治疗组总有效率97.20%,对照组总有率70.00%。两组比较差异有统计学意义(χ2=13.25,P<0.01)。治疗组疗程(4.81±0.92)d,对照组疗程(6.90±1.03)d,两组比较差异有统计学意义(t=8.31,P<0.01).用药5 d后治疗组1例出现皮疹。结论消旋卡多曲,西咪替丁联合治疗婴幼儿轮状病毒疗效显著,安全性高。
Objective To explore the therapeutical effect and security of infant rotavirus enteritis with racecadotril combined cimetidine.Methods Seventy-six patients suffering from rotavirus enteritis were devided into two groups by randomized controlled method,40 patients for the treatment,and 36 patients for control.Both groups are synthetically treated with fluid infusion,diet adjustment and Ribavirin addition.The therapy group took Racecadotril orally with Cimetidine injected,while the control group took dioctahedral smectite orally.The therapeutical effect and security of two groups were compared.Results The effective rate between two groups has significant difference（χ2=13.25,P0.01）,97.20% in treatment group while 70.22% in control group.The course treatments between two groups has significant difference（t=8.31,P0.01）,（4.81±0.92）d for treatment group while（6.90±1.03）d for control group.One case in treatment group occured skin rash 5 days after medication.Conclusion It is effective and safe in treatment of infant rotavirus enteritis with Racecadotril combined Cimetidine.
出处
《职业卫生与病伤》
2011年第2期105-106,共2页
Occupational Health and Damage
