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基于核酸适体的无标记氯化血红素荧光检测 被引量:1

Detection of Hemin by an Aptamer-based Label-free Fluorescing Molecular Switch
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摘要 介绍了核酸适体和荧光分子(噻唑橙)在生物检测中的应用,提出了一种基于核酸适体构象效应和噻唑橙作为荧光分子开关进行氯化血红素检测的荧光传感方法.实验结果表明,该方法具有较高的灵敏度. The application of aptamer and fluorescing molecular thiazole orange in the detection of biomolecules is introduced.An aptamer-based method for the sensitive detection of hemin by a label-free molecular switch(thiazole orange) is reported,which shows the characteristic of high sensitivity.
作者 高淑丽 徐慧
出处 《鲁东大学学报(自然科学版)》 2011年第2期131-134,139,共5页 Journal of Ludong University:Natural Science Edition
基金 山东省中青年科学家科研奖励基金(BS2009SW040) 鲁东大学创新团队建设项目(08-CXB001)
关键词 核酸适体 噻唑橙 氯化血红素 aptamer thiazole orange hemin
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