期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

尼美舒利再评价——兼谈如何看待非甾体抗炎药的不良反应 被引量：1

下载PDF
导出
摘要 前不久,有关媒体报道的"尼美舒利不良反应"事件震惊全国,引起公众哗然!也使一些制药企业受到影响。"尼美舒利"不良反应发生率到底有多高、多严重,近年来也一直受到业界关注。为了保证大众、尤其是儿童用药安全,提高药物警戒意识,本文就尼美舒利的不良反应并围绕非甾体抗炎药(NSAID)的安全性作一简要评价,以正视听!
作者 孙忠实 朱珠
机构地区 中国人民解放军海军总医院 中国医学科学院北京协和医院
出处 《中国医院用药评价与分析》 2011年第4期289-291,共3页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 不良反应发生率 非甾体抗炎药 尼美舒利 媒体报道 制药企业 用药安全 药物警戒 安全性
分类号 R971.1 [医药卫生—药品]
  • 相关文献

参考文献1

二级参考文献97

  • 1Andrade RJ,Lucena MI,Fernández MC,Pelaez G,Pach-koria K,García-Ruiz E,García-Mu?oz B,González-Grande R,Pizarro A,Durán JA,Jiménez M,Rodrigo L,Romero-Gomez M,Navarro JM,Planas R,Costa J,Borras A,Soler A,Salmerón J,Martin-Vivaldi R.Drug-induced liver injury:an analysis of461incidences submitted to the Spanish registry over a10-year period. Gastroenterology . 2005
  • 2Bjornsson E.Review article:drug-induced liver injury in clinical practice. Alimentary Pharmacology and Therapeutics . 2010
  • 3Drug Safety Update Volume2,Issue7,February 2009. .
  • 4Aithal GP,,Day CP.Nonsteroidal anti-inflammatory drug-induced hepatotoxicity. Clinics in Liver Disease . 2007
  • 5Watkins PB,,Seligman PJ,Pears JS,Avigan MI,Senior JR.Us-ing controlled clinical trials to learn more about acute drug-induced liver injury. Hepatology . 2008
  • 6Reuben A,Koch DG,Lee WM.Acute liver failure secondary to drug induced liver injury:causes and consequences(Ab-stract). Hepatology . 2009
  • 7EMEA:European Medicines Agency.European Medicines Agency recommends restricted use of nimesulide-containing medicinal products(on-line). http://www.emea.europa.eu/pdfs/general/direct/pr/43260407en.pdf .
  • 8ANMAT Administración Nacional de Medicamentos Ali-mentos y Tecnología Medica Disposición4087/03(on-line). http://www.anmat.gov.ar . 2009
  • 9Nota informativa de la Agencia Espa?ola del Medicamento sobre Nimesulida. http://www.osanet.euskadi.net/contenidos/informacion/notas_seg_cevime/eu_1676/adjuntos/02-05-06nimesulida.pdf . 2002
  • 10WHO Pharmaceuticals Newsletter2002,No.04. http://apps.who.int/medicinedocs/fr/d/Js4943e/3.1.html .

共引文献15

同被引文献55

  • 1Stehle JH, Von GC, Korf HW. Melatonin: A Clock- Output,A Clock-Input [ J ]. J Neuroendocrinol, 2003,15 (4) :383-389.
  • 2Dziegiel P, Podhorska-Okolow M, Zabel M. Melatonin: adjuvant therapy of malignant tumors[ J]. Med Sci Monit, 2008,14 ( 5 ) : RA64-RA70.
  • 3Reiter RJ,Tan DX, Manchester LC, et al. Medical impli- cations of melatonin: receptor-mediated and receptor- independent actions [ J ]. Adv Med Sci,2007,52 : 11-28.
  • 4Fischer TW,Slominski A,Zmijewski MA,et al. Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair [ J ]. Exp Dermatol, 2008,17 ( 9 ) : 713- 730.
  • 5Carfillo-Vico A, Guerrero JM, Lardone PJ, et al. A review of the multiple actions of melatonin on the immune system [ J ]. Endocrine,2005,27 (2) : 189-200.
  • 6Silva SO, RodriguesMR, XimenesVF, et al. Neutrophils as a specific target for melatonin and kynuramines: effects on cytokine release [ J ]. J Neuroimmunol, 2004,156 ( 1- 2) : 146-152.
  • 7Cuzzocrea S, Costantino G, Mazzon E,et al. Regulation of prostaglandin production in carrageenan-induced pleurisy by melatonin[ J]. J Pineal Res,1999,27( 1 ) :9-14.
  • 8E1-Shenawy SM, Abdel-Salam OM, Baiuomy AR, et al. Studies on the anti-inflammatory and anti-nociceptive effects of melatonin in the rat [ J ]. Pharmacol Res, 2002, 46(3 ) :235-243.
  • 9Pugazhenthi K, Kapoor M, Clarkson AN, et al. Melatonin accelerates the process of wound repair in fullthickness incisional wounds [ J ]. J Pineal Res, 2008,44 (4) : 387 -396.
  • 10Radogna F, Diederich M, Ghibelli L Melatonin: a pleiotropic molecule regulating inflarrrmfion [ J ]. Biochem Pharmacol, 2010,80(12) :1844-1852.

引证文献1

中国医院用药评价与分析
2011年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部