摘要
目的观察壮医药线点灸疗法对去卵巢家兔血清白细胞介素-2(IL-2)的影响。方法将30只健康雌性新西兰家兔随机分为正常组、假手术组、模型组、壮医药线点灸治疗组(以下简称药线组)及空线组,每组各6只。模型组、药线组、空线组行卵巢摘除术去势建立围绝经期综合征模型。假手术组只打开腹腔,不予卵巢摘除术。手术后第15 d,药线组予壮医药线点灸,空线组予空线点灸,均每日1次,连续4周。正常组、模型组和假手术组不做任何治疗。分别观察手术后第15 d、治疗后第2、4周末各组家兔血清IL-2水平变化情况。结果手术后第15 d,模型组、空线组、药线组血清IL-2水平与正常组、假手术组比较均下降,比较差异有统计学意义(P<0.05)。治疗后2周末,空线组、药线组血清IL-2水平与模型组比较有所上升,但差异无统计学意义(P>0.05)。治疗后4周末,药线组血清IL-2水平与模型组、空线组比较明显上升(P<0.05)。结论壮医药线点灸疗法可提高去卵巢家兔血清IL-2的水平,增强机体免疫功能这可能是其治疗围绝经期综合征的机制之一。
Objective To approach the effect of medicated thread moxibustion of Zhuang medicine on IL-2 in serum of ovariectomized rabbit.Methods 30 female New Zealand rabbits were randomly divided into five groups,control group,sham group,model group,medicated thread moxibustion of Zhuang medicine group（medicated thread group） and void thread group.Perimenopausal syndrome model rabbits was established by extirpation of ovaries.Medicated thread group was given medicated thread moxibustion of Zhuang medicine in the 15th days after surgery.Void thread group was given void thread moxibustion.The course was four weeks.The changes of IL-2 in rabbits serum were detected in the 15th days after surgery,two and four weeks after treatment.Results The levels of serum IL-2 in model group,medicated thread group and void thread group decreased as compared with that in control group and sham group 15 days after surgery,the difference was statistically significant（P0.05）.The levels of serum IL-2 in medicated thread group and void thread group increased as compared with model group 2 weeks after treatment,but the difference was not significant（P 0.05）.The level of serum IL-2 in medicated thread group significantly increased as compared with those in the model group and void thread group 4 weeks after treatment（P0.05）.Conclusion Medicated thread moxibustion of Zhuang medicine can increase the level of IL-2 in serum of ovariectomized rabbit,this may be one of mechanism of treating Perimenopausal syndrome.
出处
《河北中医》
2011年第4期592-594,共3页
Hebei Journal of Traditional Chinese Medicine
基金
广西壮族自治区科学技术厅广西科学基金项目(自然基金)(编号:No.桂科自0832166)
关键词
壮医
线壮灸
围绝经期
疾病模型
动物
去卵巢
家兔
白细胞介素2
Climacterium
Zhuang medicine
Medicated thread moxibustion
Rabbit model
Ovariectomized rabbit
Receptor
Interleukin 2
