摘要
目的:了解长期住院精神分裂症患者代谢综合征的患病率及其相关因素。方法:以我院住院至少6个月的精神分裂症患者为调查对象,调查其代谢指标,用世界糖尿病联盟全球统一标准定义代谢综合征。结果:住院精神分裂症患者代谢综合征的患病率为43.8%(180/411),患病率随年龄增加而增加。吸烟者较不吸烟者更易患代谢综合征;不吸烟患者中,女性的患病率(79/166,47.6%)高于男性(32/109,29.4%)(P<0.01)。非经典抗精神病药物(102/205,49.8%)较经典抗精神病药物(78/206,37.9%)更易引起代谢综合征(P<0.05)。结论:在精神科病房中应该大力倡导戒烟,并对使用非典型抗精神病药物尤其氯氮平的患者在用药过程中定期监测代谢综合征的有关指标,以减少代谢综合征的发生风险。
Objective：To investigate the prevalence of metabolic syndrome in schizophrenic long-term inpatients and its relative factors.Methods：Schizophrenic inpatients treated in our hospital for at least 6 months were investigated.Metabolic indexes were measured.The criteria of metabolic syndrome were based on the consensus definition released by the International Diabetes Federation.Results： The prevalence of metabolic syndrome was 43.8%,increased with the age.The daily smoking patients may be vulnerable to suffer from metabolic syndromes;It was higher in no-smoking female than that in no-smoking male patients（47.6% vs.29.4%,P0.01）.Atypical antic-psychotics drugs may be more easily to suffer from metabolic syndrome than typical antic-psychotics drugs（49.8 vs.37.9%,P0.05）.Conclusions： In the psychotic wards,smoking should be proposed to be given up,and as for the use of atypical anti-psychotics,especially on the patients of Clozipine,whose concerning indicators the metabolic syndrome be monitored regularly in the process of treatment,to reduce the risk of this metabolic syndrome.
出处
《中国民康医学》
2011年第9期1068-1069,1071,共3页
Medical Journal of Chinese People’s Health
