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不同剂量布地奈德混悬液经呼吸机驱动雾化吸入对AECOPD的影响 被引量:3

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摘要 目的探讨不同剂量布地奈德雾化剂对机械通气的慢性阻塞性肺疾病急性加重期(AECOPD)疗效及安全性情况。方法将31例使用呼吸机的AECOPD患者分为对照组9例(在雾化器中加入0.9%氯化钠注射液2ml+特布他林雾化液2 ml+异丙托溴铵雾化液2 ml),低剂量组11例(布地奈德雾化液2 ml+特布他林雾化液2 ml+异丙托溴铵雾化液2 ml),高剂量组11例(布地奈德雾化液4 ml+特布他林雾化液2 ml+异丙托溴铵雾化液2 ml),利用雾化操作键和雾化装置行呼吸机驱动雾化吸入,比较3组使用呼吸机时间、住重症监护病房(ICU)时间及呼吸机相关肺炎情况。结果高剂量组使用呼吸机时间和住ICU时间较对照组短(均<0.05);较低剂量组使用呼吸机时间、住ICU时间短,但差异无统计学意义(均>0.05)。3组呼吸机相关肺炎发生率差异无统计学意义(>0.05)。结论高剂量布地奈德混悬液经呼吸机驱动雾化吸入可以缩短机械通气时间和ICU住院时间。
机构地区 舟山市人民医院
出处 《现代实用医学》 2011年第3期331-332,共2页 Modern Practical Medicine
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