摘要
目的观察马来酸桂哌奇特与尼莫地平治疗高血压性脑出血术后患者的疗效。方法78例高血压脑出血的患者随机分为马来酸桂哌奇特组（39例）和尼莫地平组（39例），在微创颅内血肿穿刺引流术后第3天，马来酸桂哌奇特组采用0．9％氯化钠注射液500ml＋马来酸桂哌奇特160mg；尼莫地平组采用0．9％氯化钠注射液500ml＋尼莫地平4mg，两组患者均每天一次静脉滴注，均连用14d。观察患者的总体情况和神经性症状改善情况。结果马来酸桂哌奇特组患者总体改善率和神经性症状改善率分别为87．2％、61．5％。尼莫地平组64．1％、39．9％。结论马来酸桂哌奇特对于高血压性脑出血术后恢复期患者的临床症状和神经功能障碍的改善，明显优于尼莫地平。
Objective To observe the effects of cinepazide maleate and nimodipine in improving the neurological function in patients with hypertensive cerebral hemorrhage after microtraumatic craniopuncture. Methods Seventy-eight patients with hypertensive cerebral hemorrhage were randomly divided into 2 groups, cinepazide maleate group （39 patients） and nimodipine group（ 39 patients）. After 3 days operated with the microtraumatic craniopuncture, einepazide maleate group used the amount 160mg cinepazide maleate mixed with sodium chloride injection（500ml, concentration 0.9% ）, and the nimodipine group uesd nimodipine （4rag）mixed with the same injection. Both the patients of the 2 groups were given intravenous drip once a day, then after continuous 14 days, the general information and the improvement of nerve were observeed. Results The total improvement rate and the improvement rate of nervous symptom was 87.2% and 61.5% respectively,in comparison,the nimodipine group was 64.1% and 39.9%. Conclusion Cinepazide maleate was better than nimodipine in improving clinical symptoms and the neurological deficit of the patients with hypertensive cerebral hemorrhage after microtraumatic craniopuncture.
出处
《中国基层医药》
CAS
2011年第7期916-917,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
马来酸桂哌奇特
尼莫地平
脑出血
微创穿刺术
治疗结果
Cinepazide maleate
Nimodipine
Hypertensive cerebral hemorrhage
microtraumatic eraniopuncture
curative effect
