摘要
目的探讨大肠癌中肿瘤标记物PODOPLANIN、VEGFR-3的表达D2-40阳性淋巴管特点以及淋巴管生成,分析其与临床生物学行为及预后的关系。结论大肠癌中PODOPLANIN、VEGFR-3的表达,D2-40的升高与促进淋巴管生成和淋巴结转移,复发转移和预后不良有关。
Objective To explore the expression of PODOPLANIN And VEGF receptor （VEGFR） -3,feature of D2-40 positive lymphatic and lymphangiogcnesis to analyze their relation to clinical biological behaviour and prognosis. Conclusions The increased expression of D2-40andPODOPLANI- Nand VEGFR-3 should be related to lymphangiogenesis,lymph node metastasis, relap semetastasis and poor prognosis.
出处
《疾病监测与控制》
2011年第5期283-284,共2页
Journal of Diseases Monitor and Control
关键词
大肠肿瘤
PODOPLANIN
D2-40
VEGFR-3
淋巴管密度
转移
Carcinoma oflarge intestine
Vascular endothelial growth factorreceptor（VEGFR）-3PODOPLANIN
D2-40
Lymphatic vessel density （LVD）
Metastasis
