摘要
目的： 研究人参多糖治疗恶性胸腔积液疗效及其毒副作用。方法： ２０ 例患者皆经病理证实有恶性胸腔积液，病种分布为乳癌、肺癌、恶性间皮瘤和胃癌，人参多糖剂量为３６ ～６０ ｍｇ／ 次胸腔注射，每周一次，连用１ ～２ 周。结果： 人参多糖对恶性胸腔积液的有效率为７５ ％ ，并可增强 Ｔ 淋巴细胞及 Ｎ Ｋ 细胞活性。不良反应为一过性体温升高，最高为３８ ．５ ℃，无其他毒副作用发生。结论： 人参多糖可用于恶性胸腔积液的治疗。
OBJECTIVE:To observe the efficacy and side effects of panax ginseng polysaccharides in treatment of malignant pleural effusion.METHODS:Twenty patients with pleural effusion from cancers,such as lung,breast,stomach cancer and malignant mesothelioma,were treated with panax ginseng ploysaccharides in a weekly dose of 36～60 mg by route of intrapleural injection for 1～2 weeks.RESULTS:A 75% effective rate was obtained in treatment of maliganant pleural effusion with panax ginseng polysaccharides and the T lymphocyte and nature keller cells can also be activated by the agent with an adverse reaction of transient fever,without any other toxic reaction.CONCLUSION:Panax ginseng polysaccharides may be useful in treatment of malignant pleural effusion.
出处
《中国新药杂志》
CAS
CSCD
1999年第9期619-620,共2页
Chinese Journal of New Drugs
关键词
人参多糖
恶性胸腔积液
药物疗法
治疗
Panax ginseng polysaccharides
Malignant pleural effusion
Drug therapy
