摘要
目的分析非甾体抗炎药(NSAID)导致胃肠道黏膜损害的临床特点。方法回顾性分析218例因NSAID致胃肠道黏膜损害的临床资料。结果 NSAID致胃肠道黏膜损害常见;老年患者好发;临床症状与胃镜检查结果不甚一致;胃黏膜糜烂出血性病变为主;内科保守治疗即可愈合;住院日较短。结论 NSAID是胃肠道黏膜损害的主要原因之一,加强对NSAID的认识,正确使用,有助于减少其对胃肠道黏膜的损害。
Objective To study the clinical characteristics of gastrointestinal mucosal damage caused by non-steroidal anti-inflammatory drugs.Methods A retrospective analysis of clinical data of 218 patients with gastrointestinal mucosal damage due to non-steroidal antiinflammatory drugs had been carried out.Results NSAIDs may commonly cause gastrointestinal mucosal injuries especially in elderly patients.Their clinical symptoms and endoscopic findings were quite not similar,and they may mainly manifest as hemorrhagic and erosive lesions in gastric mucosa.These lesions can be healed by conservative treatment with shorter hospitalization.Conclusion NSAID is one of the main causes for gastrointestinal mucosal damage.It is important to realize the property of NSAIDs and rational application of this kind of drugs in order to reduce the occurrence of their gastrointestinal mucosal damage.
出处
《临床和实验医学杂志》
2011年第10期739-740,共2页
Journal of Clinical and Experimental Medicine
关键词
非甾体抗炎药
胃肠道黏膜损害
临床特点
Non-steroidal anti-inflammatory drugs
Gastrointestinal tract damage
Clinical characteristic
