摘要
目的探讨老年性白内障术中前房注射不同浓度曲安奈德（TA）控制术后炎症反应的效果。方法老年性白内障手术60例（60眼），随机分为3组，每组20眼。A组在手术结束时向前房内注射TA0．1mg／0．2mL；B组前房内注射rrA0．2mg／0．2mL。A、B组术后滴妥布霉素滴眼液，4次／d，连用1周。C组（对照组），手术结束时前房内注射灌注液，术后滴妥布霉素地塞米松滴眼液，4次／d，连用3周。术后随访1个月。术后6～8h测量眼压，术后1d、2d、7d、15d、30d观察前房细胞及房水闪光，测量眼压、检查视力及眼底。结果术后1d、2d、7d、15d、30d，3个组之间前房细胞比较（P=1），房水闪光比较（P=1），差异均无统计学意义，术后6～8h，1d、2d、7d、15d、30d，3个组之间眼压比较，差异无统计学意义。结论老年性白内障术中前房注射0．1mg／0．2mL或0．2mg／0．2mL的曲安奈德都能有效地控制术后的炎症反应，无明显不良影响，重要的是术后可以不用糖皮质激素，从而减少了频繁滴眼的麻烦，也避免了由其引起的并发症。
Objective To explore the efficacy and safety of intracameral triameinolone acetonide （TA） for controlling ocular inflammation in patients after cataract surgery. Methods Sixty patients （60 eyes） with senile cataract in our hospital were divided into group A, B and C before surgery randomly. Group A （20 eyes） and group B （20 eyes） were injected 0. 1 rag/0.2 mL and 0.2 rag/0.2 mL TA into the anterior chamber respectively during surgery. Next, group A and B were administeraned tobramycin 0.3% eyedrops 4 times per day for one week. Group C were administeraned tobramycin 0.3% and dexamethasone O. 1% eyedrops 4 times per day for three weeks with no TA. Anterior chamber eells, anterior chamber flare were assessed at postoperative day 1,2, 7, 15 and 30 by slit - lamp biomicroscopy. Visual acuity, intraocu- lar pressure, and fundus were valued at postoperative 6-8 h, day 1,2, 7, 15 and 30. Results There were no statistically significant differences in the amount of anterior chamber cells, flare and 10P in the three groups at all timepoint assessed. （ P 〉 0.05 ）. Conclusion Intracameral TA 0.1 mg/0.2 ml, 0.2 mg/ 0.2 ml can effectively control postoperative inflammation after age-related cataract surgery, and can decrease the dosage and duration of topical Drednisolone acetate.
出处
《中华眼外伤职业眼病杂志》
2011年第4期260-263,共4页
Chinese Journal of Ocular Trauma and Occupational Eye Disease
关键词
曲安奈德
前房注射
老年性白内障
手术
炎症反应
Triamcinolone acetonide
Intracameral
Senile cataract
Surgery
Inflammation
