摘要
目的:研究甲磷酸培氟沙星凝胶剂的处方、制备工艺、质量控制及稳定性。方法:采用CMC-Na为基质制成凝胶剂,用双波长紫外分光光度法测定甲磺酸培氟沙星的含量。结果:平均回收率为100.0％,RSD为0.2％,稳定性好,临床疗效较好。结论:该制剂适合于临床应用。
Objective: To study the prescription, preparation, quality control and stability of pefloxcain meylate gel. Method: CMC-Na was used as base for preparating gel. The content of pefloxacin mesylate was determined by double-wave length UV. Result: The average recovery was 100.0% with RSD 0.2% (n=4). The gel was stable. Conclusion: The pefloxacin mesylate gel was available for clinical use.
出处
《中国药师》
CAS
1999年第5期254-255,共2页
China Pharmacist
