摘要
目的:了解呼吸科下呼吸道感染的病原菌分布及常见病原菌的耐药情况。方法:采用回顾性调查的方法进行感染病例监测,对呼吸科患者发生下呼吸道的224例患者呼吸道分泌物进行细菌培养和药敏试验。结果:376例痰标本中共检出病原菌251株,主要病原菌依次为铜绿假单胞菌、鲍曼不动杆菌、金黄色葡萄球菌;不论是革兰阴性杆菌还是革兰阳性球菌均表现出了极高的多药耐药性,革兰阴性杆菌对哌拉西林/他唑巴坦、头孢哌酮/舒巴坦和亚胺培南的耐药率较低,金黄色葡萄球菌、肺炎链球菌和表皮葡萄球菌对万古霉素均未出现耐药现象。真菌占20.3%。结论:下呼吸道分离病原菌耐药现象普遍存在,临床应重视病原学检查,开展病原菌耐药性监测,合理使用抗菌药物。
Objective：To analyze the bacterial distribution and drug resistance in lower respiratory tract infection for patients in respiratory department.Method：We reviewed 224 patients suffered from lower respiratory tract infection,and made the pathogenic bacterium cultivation for secretion of the patients and then took the susceptibility test.Result：Totally 251 pathogenic bacteria were found in secretion of the patients.The major pathogenic bacteria were pseudomonas aeruginosa,baumanii and staphylococcus aureus.Drug resistances were common in Gram-negative bacilli（GNB） and Gram-positive cocci.Piperacillin/tazobactam and cefoperazone/sulbactam and imipenem were the most sensitive for GNB.S.aureus,Streptococcus pneumoniae and S.epidermi were all sensitive to vancomycin.Fungus account to 20.3%.Conclusion：Drug resistance of the pathogenicbacteria in lower respiratory tract infection is common,and it′s of great importance to emphasize pathogenic bacterium monitoring and use the antibacterials exactly.
出处
《河北医学》
CAS
2011年第5期585-589,共5页
Hebei Medicine
关键词
下呼吸道
感染
病原菌
耐药性
Lower respiratory tract； Infection； Pathogenic bacterium； Drug resistance；
