摘要
目的 明确云南省昆明市18岁以上居民脂肪肝的患病率及其主要危险因素.方法 采用随机、分层、整群抽样方法,调查昆明市4个区常住居民9500人脂肪肝的患病情况,调查内容涉及问卷、体格检查、血清生化检测以及肝脏实时超声检查.结果 昆明市受调查人员中检出脂肪肝1444例（19.08%）.经年龄和性别调整后,昆明市成人脂肪肝患病率21.57%.酒精性脂肪肝、可疑酒精性脂肪肝、非酒精性脂肪肝患病率分别为0.86%、0.69%、20.02%.单因素分析显示,脂肪肝组年龄、体重指数、腰围、腰臀比、收缩压、舒张压、空腹血糖、甘油三酯、胆固醇、低密度脂蛋白胆固醇均显著高于非脂肪肝组,而高密度脂蛋白胆固醇则明显低于非脂肪肝组,差异均有统计学意义（P＜0.001）.多元回归分析显示：甘油三酯、高密度脂蛋白胆固醇、空腹血糖、腰围、体重指数、高血压病、文化程度和性别（男性）等指标与脂肪肝密切相关.结论 昆明市成人脂肪肝患病率高,主要为非酒精性脂肪肝.脂肪肝发病率男性明显高于女性.高脂血症、超重及肥胖、糖代谢紊乱、高血压、男性等为脂肪肝危险因素.
Objective To investigate the prevalence and major risk factors of fatty liver among adult residents in Kunming. Methods A cross - sectional survey with multiple - stage stratified cluster and randomized sampling was performed. All residents aged 18 and above were invited to participate in the survey. Questionnaire, physical examination, biochemistry test and ultrasound examination of liver were undertaken. Results A total of 9500 residents took part in the survey and 1444 （ 19.08 % ） cases of fatty liver were diagnosed. The age - adjusted, sex - adjusted prevalence of fatty liver in aduh residents was 21.57% , the prevalence of alcoholic fatty liver, suspicious alcoholic fatty liver, and nonalcoholic fatty fiver were 0. 86% , 0. 69% , 20. 02% , respectively. The mean age, body mass index （BMI） , waist circumference, blood pressure, fasting - serum glucose level, triglyceride （TG） , total cholesterol（TC） , low- density lipoprotein cholesterol（ LDL- C） in the fatty liver group were significantly higher than those in the group without fatty liver（ P 〈 0. 001 ）. Logistic regression analysis demonstrated that the prevalence of fatty liver was only positively correlated to eight risk factors, including TG, HDL - C, waist circumference, BMI, fasting glucose level, hypertension, educational level, male. Conclusion There is high prevalence of fatty fiver among adult in Kunming area. And nonalcoholic fatty liver is the major type. The risk factors for the fatty liver are associated with dyslipidemia, obesity, fasting hyperglycemia, hypertension and male gender.
出处
《浙江临床医学》
2011年第5期490-493,共4页
Zhejiang Clinical Medical Journal
关键词
脂肪肝
流行病学
患病率
危险因素
Fatty liver Epidemiologieal survey Prevalence Risk factors
