摘要
目的研究高血压伴高尿酸血症患者胰岛素抵抗的情况。方法测定35例高血压伴高尿酸血症患者(A组)的空腹血糖(FBG)、空腹胰岛素(FINS)、超敏C反应蛋白(Hs-CRP)并计算胰岛素敏感性指数(IsI),同时与35例高血压无高尿酸血症患者(B组)及35例健康对照组(C组)作比较。结果 A组Hs-CRP、空腹胰岛素较B组、C组明显升高,胰岛素敏感指数较B组及C组明显下降,差异有统计学意义(P<0.05)。B组Hs-CRP、空腹胰岛素较C组明显升高,胰岛素敏感指数较C组下降,差异均有统计学意义(P<0.05)。结论高血压患者存在胰岛素抵抗,高尿酸血症可能进一步加重胰岛素抵抗,高尿酸血症与胰岛素抵抗密切相关。
Objective To explore the relationship between hyperuricemia（HUA） and insulin resistance（IR） in hypertensive patients.Methods We tested fasting blood glucose（FBG）,fasting insulin（FINS）,Hs-CRP in 35 hypertensive patients with HUA（group A）,35 normal group（group C） and in 35 hypertensive patients without HUA（group B）.We calculated insulin sensitive index（ISI）.Results There was no significant difference in fasting blood glucose among three groups（P〉0.05）,however,Hs-CRP and fasting insulin in group A were the highest among three groups（P〈0.05）;Hs-CRP and fasting insulin in group B were higher than those in group C;ISI of patients in group A significantly decreased when compared with group B and group C（P〈0.05）.Conclusions There is insulin resistance in hypertensive patients,IR is closely related to HUA.
出处
《临床医学工程》
2011年第5期699-700,共2页
Clinical Medicine & Engineering
关键词
高血压
高尿酸血症
胰岛素抵抗
Hyperuricemia
Hypertensive patients
Insulin resistance
