补肺活血胶囊对慢性阻塞性肺疾病稳定期患者的临床疗效观察被引量：21

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摘要目的探讨补肺活血胶囊对慢性阻塞性肺疾病（COPD）稳定期患者中医症候、肺功能、生存质量、1年内急性发作次数的临床疗效.方法将62例COPD稳定期Ⅲ级患者按随机数字表法分成两组：对照组30例,单纯西医治疗;治疗组32例,在西医治疗的基础上加用补肺活血胶囊.治疗3个月,对比两组疗效.结果治疗组总有效率62.5%（20,32）,对照组总有效率23.3%（7/30）,两组比较差异有统计学意义（P＜0.05）.治疗后治疗组生存质量评分、1年内急性发作次数改善方面均优于对照组（P＜0.01或＜0.05）,肺功能与对照组比较差异无统计学意义（P＞0.05）.结论 COPD稳定期在西医治疗基础上结合补肺活血胶囊治疗,能更好地缓解患者症状,预防急性发作,提高生存质量,具有较好的推广及应用价值.

作者方泓

机构地区上海中医药大学附属龙华医院呼吸科

出处《中国医师进修杂志》 2011年第13期56-57,共2页 Chinese Journal of Postgraduates of Medicine

关键词肺疾病慢性阻塞性补肺活血胶囊治疗结果

分类号 R259 [医药卫生—中西医结合]

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1Celli BR,MacNee W.Standards for the diagnosis and treatment of patients with COPD:a summary of the ATS/ERS position paper.Eur Respir J,2004,23(6):932-946.
2Agusti AC.Systemic effects of chronic obstructive pulmonary disease.Proc Am Thorac Soc,2005,2(4):367-370.
3张靖,方怀天,周世陇,陈春兰.运动锻炼配合噻托溴铵、沙美特罗／替卡松联合吸人治疗慢性阻塞性肺疾病稳定期疗效分析[J].中国医师进修杂志,2010,33(10):17-20. 被引量：10
4慢性阻塞性肺疾病诊治指南(2007年修订版)[J].中华结核和呼吸杂志,2007,30(1):8-17. 被引量：8235
5李彬,苏轮.补肺活血胶囊改善肺通气功能的临床观察[J].实用心脑肺血管病杂志,2006,14(9):728-729. 被引量：18

二级参考文献18

1有创-无创序贯机械通气多中心研究协作组.以肺部感染控制窗为切换点行有创与无创序贯机械通气治疗慢性阻塞性肺疾病所致严重呼吸衰竭的随机对照研究[J].中华结核和呼吸杂志,2006,29(1):14-18. 被引量：279
2Aaron SD, Vandemheen KL, Fergusson D,et al. Tiotropium in combination with placebo, salmeterol, or treatment of chronic obstructive pulmonary disease: trial. Ann Intern Med, 2007,146(8) : 545-555.
3Gosselink R. Breathing techniques in patients with chronic obstructive pulmonary disease (COPD). Chron Respir Dis, 2004,1 (3): 163-172.
4Pauwels RA, Buist AS, Calverley PM, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med, 2001, 163(5) : 1256-1276.
5Barnes PJ, Shapiro SD, Panwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J, 2003, 22(4): 672-688.
6Nici L, Donner C, Wouters E,et al. American Thoracic Society/ European Respiratory Society statement on pulmonary rehabilitation. Am J Respir Crit Care Med, 2006, 173(12) : 1390-1413.
7Hanania NA. Optimizing maintenance therapy for chronic obstructive pulmonary disease: strategies for improving patient-centered outcomes. Clin Ther, 2007, 29(10) : 2121-2133.
8Johnson M, Rennard S. Alternative mechanisms for long-acting beta (2)-adrenergic agonists in COPD. Chest, 2001, 120 (1): 255- 270.
9Donohue JF, van Noord JA, Bateman ED,et al. A 6-month, placebo-controlled study comparing lung function and health status changes in COPD patients treated with tiotropium or salmeterol. Chest, 9002, 122( 1 ) : 47-55.
10Griffiths TL, Burr ML, Campbell IA, et al.Resuhs at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial. Lancet, 2000, 355(9201 ): 362-368.