摘要
目的 探讨脑血管病患者血浆血栓调节蛋白（ＴＭ ）和蛋白Ｃ（ＰＣ）的水平。方法 应用ＥＬＩＳＡ 法对４５ 例脑梗死患者、１６ 例脑出血患者和对照组２４ 例健康体检者血浆ＴＭ 和ＰＣ进行了检测。结果 脑梗死组ＴＭ 水平显著高于对照组（Ｐ＜ ０．００１） ， 而脑出血组的ＰＣ水平显著高于对照组（Ｐ ＜０．０１）。结论 高水平的ＴＭ 提示脑梗死有较严重的血管内皮的损伤，高水平的ＰＣ提示脑出血患者存在ＰＣ抗凝系统的异常。
Objective To meassure the thrombomodulin and protein C levels in patiens with stroke. Mathods The thrombomodulin and protein C levels of 45 cerebral infarction,16 cerebral hemorrhage and 24 controls were mearsured by means of ELISA. Results TM was higher in cerebral infarction than in controls (P<0.001);PC was higher in cerebral hemorrhage than in controls(P<0.01). Conclusion Cerebral infarction has severe endothelial damage,and PC anti coagulation is abnomal in cerebral hemorrhage.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
1999年第5期268-269,共2页
Journal of Apoplexy and Nervous Diseases
