摘要
探讨二味康口服液抗癌及免疫调节机理。方法：采用二味康口服液不同剂量对荷Lewis肺癌小鼠进行实验。结果：二味康口服液治疗给药可使荷瘤小鼠低下的T、B淋巴细胞增殖反应，脾细胞产生IgM，血清中IgG含量及脾细胞产生IL-2恢复至接近正常水平，并促进荷瘤小鼠腹腔巨噬细胞产生IL-1和TNF。结论：二味康口服液属中药BRM（生物反应调节剂）范畴，其抗癌作用与其增强免疫功能有关。
To study the immunological machanism of antitumor activity of Erweikang(EWK) oral solution.METHODS: Immunologycal activity of EWK on mice bearing Lewis lung cancer(LLC) was investigated. RESULTS: EWK could re-convrt the low T. B. proliferous response, IgM, IgG and IL-2 to be cose to normal level, and promote IL-I and TNF preduced byPeritoneae macrophage. CONCLUSIONS: EWK belongs to the BRM of Chinese Medicine. The antitumor activity of EWK might beassociatcel eith improving the function of immune system of mice bearing LLC.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1999年第10期581-584,共4页
Chinese Journal of Hospital Pharmacy
