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精液处理后活动精子总数对宫腔内人工授精妊娠率的影响 被引量:15

Effect of the Processed Total Motile Sperm Count on the Success of Intrauterine Insemination
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摘要 目的:探讨精液处理后活动精子总数(PTMS)对宫腔内人工授精(IUI)妊娠成功率的影响。方法:回顾性分析372例不孕患者共816个IUI周期的临床资料。按照PTMS数量将IUI周期分成4个区间组:PTMS<3×106(A组),3×106-5×106(B组),5×106-10×106(C组),>10×106(D组),分别比较各组间的IUI周期妊娠率。结果:816个IUI周期共获得110例妊娠,总周期妊娠率为13.5%。不同PTMS分组的周期妊娠率分别为3.8%,4.2%,14.8%和14.3%。其中A组、B组的周期妊娠率均显著低于C组和D组(P<0.05)。结论:PTMS是男性生育力评估及助孕方式选择的重要参考依据。当PTMS超过5×106时,可首选IUI治疗。 Objective:To assess the relationship between the processed total motile sperm(PTMS) count and intrauterine insemination(IUI) outcome.Methods:The clinical data of 372 infertile couples who underwent 816 IUI cycles was analyzed by a retrospective study.According to the PTMS count,the patients were divided into 4 groups:3×106(group A),3×106 to 5×106(group B),5×106 to 10×106(group C) and 10×106(group D).The difference of pregnancy rate per cycle among the subgroups was then compared by statistical analysis.Results:A total of 110 clinical pregnancies were obtained and the overall pregnancy rate was 13.5% per cycle.The pregnancy rate of each group was 3.8%,4.2%,14.8% and 14.3%,respectively.The pregnancy rate per cycle in groups A or group B was significantly lower than that in groups C and D(P0.05).Conclusion:PTMS assay is an important reference for male fertility assessment and the choice of assisted reproductive technology.In our opinion,IUI treatment is recommended to be performed when PTMS is 5×106.
出处 《生殖与避孕》 CAS CSCD 北大核心 2011年第4期246-249,共4页 Reproduction and Contraception
基金 广州市卫生局重点项目 项目号:2005-ZDi-02
关键词 宫腔内人工授精(IUI) 妊娠率 处理后活动精子总数(PTMS) intrauterine insemination pregnancy rate processed total motile sperm count
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