摘要
目的:探讨胃肠间质瘤的CT表现与恶性程度相关性。方法:分析经手术病理及免疫组织化学证实的45例GIST的CT资料,分析肿瘤大小、形态、轮廓、生长方式、强化程度及坏死情况。分析比较肿瘤恶性的CT征象。采用SPSS13.0统计软件及Fisher's exact test分析。结果:胃部间质瘤25例、小肠13例、直肠1例、腹腔肠系膜4例、部位不明确2例,2例见远处转移。2位腹部影像医师对CT结果独立分级。肿瘤大小、形态、轮廓、坏死情况、生长方式与恶性程度有统计学意义(P<0.05),肿瘤部位、强化方式与恶性程度无统计学意义。结论:胃肠间质瘤的CT表现具有一定的特征性,CT表现有助于判断肿瘤恶性程度,对肿瘤的诊断、分期和治疗有显著的价值。
Purpose:To analyze the computed tomographic features and evaluate the correlation between imaging presentation and malignant risk of gastrointestinal stromal tumors(GISTs).Methods:The abdominal CT characteristics and pathological manifestations of 45 surgically treated patients with histologically and immunohistochemically confirmed GISTs were retrospectively analyzed.Images were assessed for the size,morphous,contour,growth pattern,degree of enhancement,and necrosis of the tumors.The findings of benign and malignant GISTs were compared.Statistical analysis was performed by SPSS13.0 and Fisher's exact test.Results:The tumors were found to originate from stomach(n=25),small bowel(n=13),rectum(n=1),mesentery and omentum(n=4),indefinite site(n=2),and with metastases(n=2).Computerized tomography findings were graded for the GISTs by two radiologists.There was a significant correlation between certain CT features(tumor size,contour,morphous,necrosis and growth pattern) and tumor risk stratification(P0.05).However,tumor location and degree of enhancement were found to have no statistical significance for high-risk malignant GISTs.Conclusion: GISTs have some specific CT findings which could be helpful for assessing tumor risk stratification.The CT scan is valuable in the diagnosis,staging,and treatment planning of GISTs.
出处
《中国医学计算机成像杂志》
CSCD
北大核心
2011年第2期135-139,共5页
Chinese Computed Medical Imaging
关键词
胃肠间质瘤
X线计算机
体层摄影术
病理学
Gastrointestinal Stromal Tumors
X-ray computed
tomography
Pathology