摘要
目的:探讨头颈部非霍奇金淋巴瘤的临床特点、病理分型、误诊原因、治疗及预后,为该病的早期诊断及治疗提供经验。方法:对138例原发于头颈部的非霍奇金淋巴瘤的临床表现、治疗及预后等进行回顾性分析。结果:男性发病率高于女性(男:女=1.26:1),B细胞非霍奇金淋巴瘤发病率(86.2%)明显高于T细胞非霍奇金淋巴瘤(13.8%),首发症状以无痛性肿块(71.7%)多见,首发部位依次为颈部、下颌下区、腮腺、面部皮肤、颌骨、舌部、腭部,治疗主要以手术+化疗为主,患者5年生存率为59.4%。结论:非霍奇金淋巴瘤在头颈部表现呈多样化,误诊率较高,应予以重视,以提高早期诊断及治疗水平。
PURPOSE： To analyze the clinical features,pathological classification,causes of misdiagnosis,treatment and prognosis of non-Hodgkin＇s lymphoma（NHL） originated in head and neck and to afford experience in early diagnosis and treatment.METHODS： The clinical manifestation,treatment and prognosis of 138 cases of primary head and neck NHL were studied retrospectively.RESULTS： The incidence in male was higher than that in female（male ：female=1.26：1）.Among non-Hodgkin＇s lymphomas,86.2% were neoplasms originating from B lymphocytes,which was remarkably higher than those originating from T lymphocyte（13.8%）.The early symptom was mainly painless mass（71.7%）.The primary location was in the following order： cervical region,submandibular region,parotid gland,skin of face,maxilla and mandible,tongue and palate.The main treatment was multimodal therapy（chemotherapy and operations）.The five-year survival rate was 59.4%.CONCLUSIONS： The clinical manifestation of head and neck NHL is not specific and has a high misdiagnosis rate,so we must pay more attention to improve the early diagnosis and treatment of NHL.
出处
《上海口腔医学》
CAS
CSCD
2011年第2期179-182,共4页
Shanghai Journal of Stomatology
关键词
非霍奇金淋巴瘤
头颈部
诊断
治疗
Non-Hodgkin＇s lymphoma
Head and neck
Diagnosis
Treatment
