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泰素帝和顺铂联合放疗同步治疗56例中晚期宫颈癌的观察与护理 被引量:2

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摘要 目的观察泰素帝和顺铂同步放化疗对中晚期宫颈癌的疗效与护理。方法将56例中晚期(Ⅱb~Ⅳa期)宫颈癌患者随机分为2组:单纯放疗组(RT组)28例,TP方案联合放疗组(RT+C组)28例。2组放疗方法相同。(RT+C)组在放疗开始每周一次顺铂20mg iv drop d1,泰素帝35 mg/m2 iv drop d1,共4~5周,并常规给予止吐药物及适当水化,口服地塞米松防过敏反应,2组患者从治疗开始均每日服用甲地孕酮160mg至治疗结束。结果 (RT+C)组完全缓解(CR)18例(64.3%),部分缓解(PR)10例(35.7%),有效率(CR+PR)100%;RT组CR9例(32.1%),PR11例(39.3%),SD8例(28.6%),有效率(CR+PR)71.4%,(RT+C)组的CR及有效率均高于RT组,差异有统计学意义。结论在正确使用泰素帝和顺铂同步放化疗治疗及精心护理下,中晚期宫颈癌患者取得较好的治疗效果。
出处 《当代护士(中旬刊)》 2011年第5期89-91,共3页 Modern Nurse
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